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Moreover, NLRP3 inflammasome activation through active caspase-1 cleaves gasdermin D (GSDMD), that initiates pyroptosis leading to upregulation of IL-1β [128]

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Side Effects of Ozempic and Wegovy: What to Expect As your dose increases, common side effects include: Nausea Constipation or diarrhoea Acid reflux or bloating These symptoms usually improve over time with hydration and gradual dosage increases

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